Growth Suppression with Acetazolamide

High-altitude corneal oedema associated with acetazolamide.

Brain SPECT imaging with acetazolamide challenge.

The patient was a 69-y-old man who, 37 d earlier, had a 4-d-long evolving onset of headache, dizziness, acute personality changes, visual changes, and weakness. Unspecified imaging was obtained at an outside facility, and he was diagnosed with an intracerebral stenosis. Subsequently, he was given aspirin and clopidogrel (Plavix; Bristol-Myers Squibb/Sanofi Pharmaceuticals Partnership) and told ...

Acetazolamide: Treatment of Psychogenic Polydipsia

We are reporting a case of psychogenic polydipsia from a State of Ohio psychiatric hospital. The patient has a known five-year history of psychogenic polydipsia with recurrent hyponatremia and has been diagnosed with schizoaffective disorder bipolar type 1, according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria, for the past two decades. There was...

Acetazolamide-based fungal chitinase inhibitors

Chitin is an essential structural component of the fungal cell wall. Chitinases are thought to be important for fungal cell wall remodelling, and inhibition of these enzymes has been proposed as a potential strategy for development of novel anti-fungals. The fungal pathogen Aspergillus fumigatus possesses two distinct multi-gene chitinase families. Here we explore acetazolamide as a chemical sc...

Fatal reaction to acetazolamide.

ACETAZOLAMIDE is known to produce many minor side-effects when given for any length of time. Becker and Middleton (1955) have described the following in seventy patients receiving long-term acetazolamide for glaucoma: paresthesiae 61 per cent., gastrointestinal disturbances 49 per cent., excessive fatigue 16 per cent., urinary disturbances 4 per cent., hearing loss 3 per cent., leucopenia 3 per...